TANUH-CBR IndiNeuroFM

TANUH-CBR IndiNeuroFM

TANUH-CBR IndiNeuroFM

A Multimodal AI Platform for India-Specific Neurological Intelligence

A Multimodal AI Platform for India-Specific Neurological Intelligence

A Multimodal AI Platform for India-Specific Neurological Intelligence

Overview

Overview

Overview

Neurological disorders are complex, data-intensive, and deeply influenced by population-specific factors such as anatomy, ageing patterns, and disease prevalence. However, most existing medical AI models are trained on Western datasets, making them poorly suited for Indian populations.

India presents unique neurological characteristics—from differences in brain structure and ageing trajectories to higher prevalence of conditions like neuro-tuberculosis and nutritional deficiencies. These gaps result in reduced accuracy in diagnosis, limited clinical relevance, and inequitable healthcare outcomes.

This creates a critical need for a sovereign, India-specific medical foundation model that can understand and operate within the country’s clinical and demographic realities.

Neurological disorders are complex, data-intensive, and deeply influenced by population-specific factors such as anatomy, ageing patterns, and disease prevalence. However, most existing medical AI models are trained on Western datasets, making them poorly suited for Indian populations.

India presents unique neurological characteristics—from differences in brain structure and ageing trajectories to higher prevalence of conditions like neuro-tuberculosis and nutritional deficiencies. These gaps result in reduced accuracy in diagnosis, limited clinical relevance, and inequitable healthcare outcomes.

This creates a critical need for a sovereign, India-specific medical foundation model that can understand and operate within the country’s clinical and demographic realities.

Neurological disorders are complex, data-intensive, and deeply influenced by population-specific factors such as anatomy, ageing patterns, and disease prevalence. However, most existing medical AI models are trained on Western datasets, making them poorly suited for Indian populations.

India presents unique neurological characteristics—from differences in brain structure and ageing trajectories to higher prevalence of conditions like neuro-tuberculosis and nutritional deficiencies. These gaps result in reduced accuracy in diagnosis, limited clinical relevance, and inequitable healthcare outcomes.

This creates a critical need for a sovereign, India-specific medical foundation model that can understand and operate within the country’s clinical and demographic realities.

Our Solution

Our Solution

Our Solution

IndiNeuroFM is a Unified Multimodal Medical Foundation Model (UMMFM) designed specifically for the Indian brain.

It integrates imaging, clinical data, and biomarkers to enable accurate diagnosis, prognosis, and research across neurological conditions.

The platform acts as a multimodal bridge, connecting different forms of medical data to generate clinically meaningful insights at scale.

IndiNeuroFM is a Unified Multimodal Medical Foundation Model (UMMFM) designed specifically for the Indian brain.

It integrates imaging, clinical data, and biomarkers to enable accurate diagnosis, prognosis, and research across neurological conditions.

The platform acts as a multimodal bridge, connecting different forms of medical data to generate clinically meaningful insights at scale.

IndiNeuroFM is a Unified Multimodal Medical Foundation Model (UMMFM) designed specifically for the Indian brain.

It integrates imaging, clinical data, and biomarkers to enable accurate diagnosis, prognosis, and research across neurological conditions.

The platform acts as a multimodal bridge, connecting different forms of medical data to generate clinically meaningful insights at scale.

Solution 1: Multimodal Brain Intelligence Engine

Solution 1: Multimodal Brain Intelligence Engine

Solution 1: Multimodal Brain Intelligence Engine

A foundation model that enables cross-modal understanding and generation across medical data types.

Capabilities:

  • Convert brain scans (MRI/CT) into structured clinical reports

  • Generate cross-modality imaging (MRI ↔ CT)

  • Create synthetic brain imaging from clinical prompts

  • Learn unified representations across imaging, text, and metadata

A foundation model that enables cross-modal understanding and generation across medical data types.

Capabilities:

  • Convert brain scans (MRI/CT) into structured clinical reports

  • Generate cross-modality imaging (MRI ↔ CT)

  • Create synthetic brain imaging from clinical prompts

  • Learn unified representations across imaging, text, and metadata

A foundation model that enables cross-modal understanding and generation across medical data types.

Capabilities:

  • Convert brain scans (MRI/CT) into structured clinical reports

  • Generate cross-modality imaging (MRI ↔ CT)

  • Create synthetic brain imaging from clinical prompts

  • Learn unified representations across imaging, text, and metadata

Goals

Goals

Goals

Improve diagnostic accuracy in neurological imaging

Improve diagnostic accuracy in neurological imaging

Improve diagnostic accuracy in neurological imaging

Reduce dependency on manual interpretation

Reduce dependency on manual interpretation

Reduce dependency on manual interpretation

Enable scalable clinical decision support

Enable scalable clinical decision support

Enable scalable clinical decision support

Key Features of the Solution:

Key Features of the Solution:

Key Features of the Solution:

Multimodal AI combining imaging, text, and metadata

Multimodal AI combining imaging, text, and metadata

Multimodal AI combining imaging, text, and metadata

3D volumetric understanding of brain scans

3D volumetric understanding of brain scans

3D volumetric understanding of brain scans

Structured “Neuro-Tuple” data architecture

Structured “Neuro-Tuple” data architecture

Structured “Neuro-Tuple” data architecture

Foundation model trained on India-specific datasets

Foundation model trained on India-specific datasets

Foundation model trained on India-specific datasets

Solution 2: Cognitive Impairment Staging & Prognostics

Solution 2: Cognitive Impairment Staging & Prognostics

Solution 2: Cognitive Impairment Staging & Prognostics

Uses multimodal biomarkers to classify and predict stages of cognitive impairment.

Capabilities:

  • Classify Mild Cognitive Impairment (MCI) stages

  • Predict progression trajectories of cognitive decline

  • Integrate clinical, cognitive, imaging, and biochemical data

Uses multimodal biomarkers to classify and predict stages of cognitive impairment.

Capabilities:

  • Classify Mild Cognitive Impairment (MCI) stages

  • Predict progression trajectories of cognitive decline

  • Integrate clinical, cognitive, imaging, and biochemical data

Uses multimodal biomarkers to classify and predict stages of cognitive impairment.

Capabilities:

  • Classify Mild Cognitive Impairment (MCI) stages

  • Predict progression trajectories of cognitive decline

  • Integrate clinical, cognitive, imaging, and biochemical data

Goals

Goals

Goals

Enable early detection of cognitive decline

Enable early detection of cognitive decline

Enable early detection of cognitive decline

Support proactive intervention and care planning

Support proactive intervention and care planning

Support proactive intervention and care planning

Differentiate normal ageing from pathological conditions

Differentiate normal ageing from pathological conditions

Differentiate normal ageing from pathological conditions

Key Features of the Solution:

Key Features of the Solution:

Key Features of the Solution:

Large-scale multimodal dataset (clinical + imaging + biomarkers)

Large-scale multimodal dataset (clinical + imaging + biomarkers)

Large-scale multimodal dataset (clinical + imaging + biomarkers)

Population-specific modelling across rural and urban cohorts

Population-specific modelling across rural and urban cohorts

Population-specific modelling across rural and urban cohorts

Explainable AI using SHAP for transparent decision-making

Explainable AI using SHAP for transparent decision-making

Explainable AI using SHAP for transparent decision-making

Clinically grounded biomarker prioritization

Clinically grounded biomarker prioritization

Clinically grounded biomarker prioritization

Impact & Vision

Impact & Vision

Impact & Vision

Current Impact:

Current Impact:

Current Impact:

Building India’s first sovereign neurological foundation model

Training on 70,000+ brain imaging volumes across MRI and CT modalities

Leveraging 20,000+ multimodal clinical, cognitive, and biomarker data points

Advancing state-of-the-art performance in:

  • Imaging segmentation and analysis

  • Clinical report generation

  • Cognitive impairment classification (>85% target accuracy)

Enabling explainable AI for transparent and clinically interpretable decisions

Powering multi-institutional collaboration across hospitals, diagnostics, and research centres in India

Addressing population-specific gaps in diagnosis for conditions like neuro-infections, nutritional deficiencies, and atypical ageing patterns

Building India’s first sovereign neurological foundation model

Training on 70,000+ brain imaging volumes across MRI and CT modalities

Leveraging 20,000+ multimodal clinical, cognitive, and biomarker data points

Advancing state-of-the-art performance in:

  • Imaging segmentation and analysis

  • Clinical report generation

  • Cognitive impairment classification (>85% target accuracy)

Enabling explainable AI for transparent and clinically interpretable decisions

Powering multi-institutional collaboration across hospitals, diagnostics, and research centres in India

Addressing population-specific gaps in diagnosis for conditions like neuro-infections, nutritional deficiencies, and atypical ageing patterns

Building India’s first sovereign neurological foundation model

Training on 70,000+ brain imaging volumes across MRI and CT modalities

Leveraging 20,000+ multimodal clinical, cognitive, and biomarker data points

Advancing state-of-the-art performance in:

  • Imaging segmentation and analysis

  • Clinical report generation

  • Cognitive impairment classification (>85% target accuracy)

Enabling explainable AI for transparent and clinically interpretable decisions

Powering multi-institutional collaboration across hospitals, diagnostics, and research centres in India

Addressing population-specific gaps in diagnosis for conditions like neuro-infections, nutritional deficiencies, and atypical ageing patterns

Future Vision:

Future Vision:

Future Vision:

To establish a sovereign, India-first AI infrastructure for neurological healthcare

To enable accurate, equitable, and population-specific diagnosis across diverse Indian contexts

To build a unified multimodal intelligence layer connecting imaging, clinical data, and biomarkers

To support early detection and proactive care for neurological and cognitive disorders

To create a scalable foundation for future medical AI innovation in India and the Global South

To drive clinically grounded, transparent, and ethical AI systems for real-world deployment

To establish a sovereign, India-first AI infrastructure for neurological healthcare

To enable accurate, equitable, and population-specific diagnosis across diverse Indian contexts

To build a unified multimodal intelligence layer connecting imaging, clinical data, and biomarkers

To support early detection and proactive care for neurological and cognitive disorders

To create a scalable foundation for future medical AI innovation in India and the Global South

To drive clinically grounded, transparent, and ethical AI systems for real-world deployment

To establish a sovereign, India-first AI infrastructure for neurological healthcare

To enable accurate, equitable, and population-specific diagnosis across diverse Indian contexts

To build a unified multimodal intelligence layer connecting imaging, clinical data, and biomarkers

To support early detection and proactive care for neurological and cognitive disorders

To create a scalable foundation for future medical AI innovation in India and the Global South

To drive clinically grounded, transparent, and ethical AI systems for real-world deployment

Team & Collaborators

Team & Collaborators

Team & Collaborators

Investigators

Investigators

Investigators

Phaneendra K. Yalavarthy

Phaneendra K. Yalavarthy

Phaneendra K. Yalavarthy

Professor
Department of Computational and Data Sciences, IISc

Personal website

Professor
Department of Computational and Data Sciences, IISc

Personal website

Professor
Department of Computational and Data Sciences, IISc

Personal website

Ambedkar Dukkipati

Ambedkar Dukkipati

Ambedkar Dukkipati

Professor
Computer Science and Automation, IISc

Personal website

Professor
Computer Science and Automation, IISc

Personal website

Professor
Computer Science and Automation, IISc

Personal website

K. V. S. Hari

K. V. S. Hari

K. V. S. Hari

Director
Centre for Brain Research, IISc

Personal website

Director
Centre for Brain Research, IISc

Personal website

Director
Centre for Brain Research, IISc

Personal website

Sindura Ganapathi

Senior Advisor
Centre for Brain Research, IISc

Personal website

Sindura Ganapathi

Sindura Ganapathi

Senior Advisor
Centre for Brain Research, IISc

Personal website

Senior Advisor
Centre for Brain Research, IISc

Personal website

Team

Team

Team

Saurabh Sharma

Saurabh Sharma

Saurabh Sharma

Post-Doctoral Fellow

Post-Doctoral Fellow

Post-Doctoral Fellow

Addanki Chinni

Addanki Chinni

Addanki Chinni

Tehnical Staff Member

Tehnical Staff Member

Tehnical Staff Member

Bhavani Sankar Vijayakatu

Bhavani Sankar Vijayakatu

Bhavani Sankar Vijayakatu

Technical Staff Member

Technical Staff Member

Technical Staff Member

Naveen K. Pallekonda

Naveen K. Pallekonda

Naveen K. Pallekonda

Early Stage Researcher

Early Stage Researcher

Early Stage Researcher

Sai Keerthana Neriyanuri

Sai Keerthana Neriyanuri

Sai Keerthana Neriyanuri

Intern

Intern

Intern

Partners and Collaborators

Partners and Collaborators

Get Involved

Get Involved

Get Involved

We welcome collaborations with researchers, public health organisations, and technology partners.

We welcome collaborations with researchers, public health organisations, and technology partners.

We welcome collaborations with researchers, public health organisations, and technology partners.

Contact us at indineurofm@tanuh.ai

Contact us at indineurofm@tanuh.ai

Contact us at indineurofm@tanuh.ai

The AI Centre of Excellence in Healthcare

AI Centre of Excellence in Healthcare
Indian Institute of Science
Seventh Floor, TCS Smart-X Hub
Bengaluru, India - 560 012  

Email: info@tanuh.ai

Telephone: (080) 2293 4106 | (080) 2293 4107

2026 by TANUH

The AI Centre of Excellence in Healthcare

AI Centre of Excellence in Healthcare
Indian Institute of Science
Seventh Floor, TCS Smart-X Hub
Bengaluru, India - 560 012  

Email: info@tanuh.ai

Telephone: (080) 2293 4106 | (080) 2293 4107

2026 by TANUH

The AI Centre of Excellence in Healthcare

AI Centre of Excellence in Healthcare
Indian Institute of Science
Seventh Floor, TCS Smart-X Hub
Bengaluru, India - 560 012  

Email: info@tanuh.ai

Telephone: (080) 2293 4106 | (080) 2293 4107

2026 by TANUH